For 170 years, doctors have knocked out patients with a cocktail of gases or injections before surgery. Those drugs haven鈥檛 changed much in that time. And they have many side effects and dangers. How anesthesia actually works also remains one of the great mysteries of neuroscience. This leaves plenty of opportunity for the type of innovation that a 澳门六合彩资料库 Davis professor is pioneering.
knows how to make these drugs safer for the lungs, heart and other systems, leading to fewer of the costly complications from surgeries. In his research at 澳门六合彩资料库 Davis, he has discovered a way to target specific neuroreceptors with new drug agents. This could revolutionize the medical field.
But Brosnan has a few challenges before this technology can be used on humans. For one, Brosnan is a veterinarian.
Bringing his science to market takes entrepreneurship
To bring his science to market, Brosnan has needed collaborators, connections and business advice. He presented his idea at the , hosted by the 澳门六合彩资料库 Davis . There he met fellow 澳门六合彩资料库 Davis alumnus and entrepreneur Mark Holman, and together they planted the seed for what would later become a new venture: .
鈥淭hey represent the interdisciplinary vision of this university,鈥 says Professor Andrew Hargadon, the institute鈥檚 founder and faculty director. 鈥淪cientists working across fields and with industry to turn their leading scientific research into practical and world-changing applications.鈥
One medicine for animals and humans
Though Brosnan specializes in veterinary anesthesia and analgesia, his research has promising potential for use in humans. It鈥檚 an example of the cross-disciplinary One Health initiative.
Physicians, veterinarians, dentists, nurses and others working in science, health and the environment are collaborating to advance new breakthroughs.
$1 million grant from National Institutes of Health
Brosnan began with a $1 million grant for his lab from the . Holman has since licensed the technology from 澳门六合彩资料库 Davis for Expanesthetics, and he has raised almost $3 million from private investors. Holman has been growing the company鈥檚 staff, which now includes a chief operating officer: Shane Austin, a 澳门六合彩资料库 Davis biomedical engineering graduate.
With clinical trials and the federal review process, it could take more than a decade and up to $350 million to get a new drug from the lab to surgical suites. Holman is ready for the long haul and confident about bringing multiple new drugs to market based on Brosnan鈥檚 research.
鈥淭here is a lot of room for improvement in the drugs that we use,鈥 he said. 鈥淪urgical anesthesia in the 21st century should look completely different than it did in the 1840s.鈥
by the 澳门六合彩资料库 Davis Graduate School of Management
Brad Hooker is a writer for the 澳门六合彩资料库 Davis Graduate School of Management, where he鈥檚 advancing the content strategy for the school鈥檚 many business research and education topics.